Growth without growth hormone in combined pituitary hormone deficiency caused by pituitary stalk interruption syndrome
نویسندگان
چکیده
منابع مشابه
Growth without growth hormone in combined pituitary hormone deficiency caused by pituitary stalk interruption syndrome
Growth hormone (GH) is an essential element for normal growth. However, reports of normal growth without GH have been made in patients who have undergone brain surgery for craniopharyngioma. Normal growth without GH can be explained by hyperinsulinemia, hyperprolactinemia, elevated leptin levels, and GH variants; however, its exact mechanism has not been elucidated yet. We diagnosed a female pa...
متن کاملDiagnosis of growth hormone (GH) deficiency: comparison of pituitary stalk interruption syndrome and transient GH deficiency
BACKGROUND Most patients with childhood non-organic growth hormone (GH) deficiency (GHD) produce a normal GH peak as young adults. Our objectives were to better define this transient GHD and evaluate the factors influencing the growth response of patients with pituitary stalk interruption syndrome (PSIS). METHODS We studied 72 prepubertal patients with a GH peak < 6.7 ng/ml after 2 stimulatio...
متن کاملVitamin D in children with growth hormone deficiency due to pituitary stalk interruption syndrome
BACKGROUND Recent studies have shown a relationship between vitamin D status and growth hormone (GH) and insulin-like growth factor 1 (IGF1). The objective of this study was to assess vitamin D status in children with GH deficiency due to pituitary stalk interruption syndrome (PSIS) and to investigate the relationship between 25-hydroxyvitamin D (25OHD) and 1,25-dihydroxyvitamin D (1,25 (OH) 2D...
متن کاملGrowth Hormone Deficiency in Autoimmune Pituitary Disorders
GH deficiency (GHD) can manifest in childhood as growth failure, delayed bone age and slow growth velocity, while in adults the picture is more complex and is characterised by negative effects on body composition, cardiovascular functions and poor quality of life. Life expectancy is reduced in adult patients with GHD as a consequence of cardiovascular and cerebrovascular events. Most, if not al...
متن کاملPituitary Disorders Pediatric Growth Hormone Deficiency
Optimal therapy of growth disorders depends on accurate diagnosis and clear goals for therapy. Understanding normal patterns of growth hormone (GH) and insulin-like growth factor secretion are necessary to appreciate the different hormone pattern induced by therapy. Finally, monitoring efficacy and safety, identifying interfering factors, and adjusting doses, are all part of optimizing GH thera...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Pediatric Endocrinology & Metabolism
سال: 2017
ISSN: 2287-1012,2287-1292
DOI: 10.6065/apem.2017.22.1.55